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The precise identification and analysis of metabolites using mass spectrometry (MS), infra-red (IR), and Raman spectroscopy, as well as nuclear magnetic resonance (NMR) in combination with modern computational approaches, can further advance the progress in the discipline of metabolomics (19, 20)

Although many circulating factors cannot cross the BBB, they can still affect the brain by binding to receptors on BBB endothelial cells, such as growth differentiation factor 11 (GDF11) [198, 199]

Neuroinflammation and oxidative stress are not unique to autism
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