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Through interactions with neurons, microglia regulate crucial processes such as neuronal activity, synapse formation and survival, and the remodeling of presynaptic circuit (Badimon et al., 2020
SAH level was correlated with methyltransferase inhibition and cognitive impairment in PD and AD patients (Kennedy et al
reported reduced expression of genes responsible for melanin synthesis in the hair folliclesuch as TYR, melan-A (MLANA), premelanosome protein (PMEL), TYRP1, SLC45A2, KIT, G proteincoupled receptor 143 (GPR143), and OCA2in patients with premature graying.15 UV radiation UV radiation plays an important role in hair graying by stimulating the production of free radicals
doi: 10.3389/fnagi.2022.917629 151 WangX.SunG.FengT.ZhangJ.HuangX.WangT.et al
