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However, some users report mild side effects such as dizziness, flushing, and occasional headaches

10.1073/pnas.252649099
The proposed aspects in the neuroinflammatory activity of this vitamin including the regulation of Alzheimer-associated enzymes such as COX-2, 5-lipoxygenase (5-LOX), and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Block, 2008

Thirdly, the current preclinical studies lack standardized outcome measures, meaning more systematic in vivo studies are required to validate the efficacy and safety of mitochondria-targeted ferroptosis modulators
