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Reduced HPA axis function resulting in low cortisol levels is common in PTSD, fibromyalgia, chronic fatigue syndrome, certain affective disorders, and individuals with high psychosocial burnout. Other specific terms for different stress-related HPA axis phenomena include hypercortisolism, loss of HPA circadian function, and low circulating DHEA(S)

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& Bunn, H

In contrast, impairment of GH signaling due to insulin deficiency cannot generally be compensated by GH hypersecretion