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Around months 3 to 6, some users notice telogen effluvium temporary hair shedding linked to rapid weight change and nutrition gaps, not the medication directly

In some people, the gut may respond with more sensitivity or changes in intestinal fluid balance, which can lead to looser stools or diarrhea, she explains

[7] [8] Criteria and service requirements should be confirmed with the current TA875 guidance

The main exception to this rule is the GLP-1 class (like semaglutide, tirzepatide, or retatrutide), which may be used for longer under proper supervision since the studies and pharmacology support extended duration