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The glucagon-like peptide-1 receptor agonist exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis

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Although renin was discovered more than a century ago and the detection of angiotensin I, angiotensin II and aldosterone in the 50s allowed the definition of the classical RAAS pathway from 1961 (19), the research in this field continues and new evidence has recently emerged